The Animal Core serves as a central resource for all animals used by all investigators in the Program Project. Core personnel are responsible for maintaining up-to-date assessments of animal requirements for all Projects. They ensure timely ordering, delivery, and proper husbandry of animals. All animal procedures are conducted and/or supervised by Animal Core personnel.
Most animals used in the Program Project have their blood pressure carefully and reliably quantified by Animal Core personnel either directly (radiotelemetry) or indirectly (tail-cuff sphygmomanometry) as part of each experimental protocol. A major advantage of Animal Core is that it facilitates the most efficient use of animals by Program Investigators.
Our in vivo protocols also are designed to maximize the amount of data collected from a single animal. This is achieved through use of long-term repeated measurements of cardiovascular parameters where possible, rather than studying separate groups of animals at each time point of interest.